CARDIOVASCULAR PHYSIOLOGY CONCEPTS
LV Volume (ml)
Reduced ventricular filling time caused by
tachycardia leads to a decrease in EDV and
SV This preload change alone, however, will
not alter ESV The addition of a fall in arterial
pressure decreases afterload on the ventricle,
which independently increases stroke volume
and reduces ESV This can lead to a further
decrease in EDV The net effect of these two
conditions will be a large reduction in EDV
coupled with a small reduction in ESV, and
large fall in stroke volume. Because of the
hypotension (both systolic and diastolic), the
ejection phase of the pressure-volume loop
starts at a lower pressure, and the peak ven-
tricular systolic pressure is also reduced.
LV Volume (ml)
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